Obsessive-Compulsive and Related Disorders

Obsessive-Compulsive Disorder (OCD)

•    Definitions:

o    Obsessions: intrusive, unwanted, repetitive thoughts, images, or urges causing distress 

                                                                        (e.g., contamination, symmetry, harm)

o    Compulsions: repetitive behaviours or mental acts to reduce distress 

                                                                        (e.g., washing, checking, counting)

•    Clinical features:

o    Insight usually preserved, though can vary; poor insight = worse prognosis

o    Symptoms often ego-dystonic (experienced as alien to self)

•    Treatment:

o    First-line: CBT with exposure and response prevention (ERP)

o    SSRIs (e.g., fluoxetine, sertraline) at higher doses, and longer treatment trial (≥12 weeks before judging efficacy)

o    Clomipramine (TCA) sometimes used if SSRI-resistant

o    Severe cases: consider augmenting with antipsychotics (e.g., risperidone)

•    Pearls:

o    Check for comorbid depression (common)

o    Avoid benzodiazepines; may worsen long-term course


Body Dysmorphic Disorder (BDD)

•    Features:

o    Preoccupation with perceived defect or flaw in appearance (often minimal or not observable to others)

o    Repetitive behaviours: mirror checking, excessive grooming, reassurance seeking

o    Commonly affects face, skin, hair

•    Impact:

o    Significant distress or impairment in social, occupational, or other areas

o    High rates of comorbid depression, suicidal ideation

•    Treatment:

o    CBT focusing on cognitive restructuring and exposure

o    SSRIs helpful, often at higher doses


Trichotillomania (Hair-Pulling Disorder)

•    Features:

o    Recurrent pulling out of hair (scalp, eyebrows, eyelashes) noticeable hair loss

o    Repeated attempts to stop

o    Can be accompanied by tension before pulling and relief after

•    Treatment:

o    CBT (habit reversal training)

o    SSRIs have variable benefit


Hoarding Disorder

•    Features:

o    Persistent difficulty discarding possessions regardless of value

o    Perceived need to save items; distress with discarding

o    Results in clutter, impairing living spaces and function

•    Treatment:

o    CBT focused on hoarding

o    SSRIs less consistently effective compared to classic OCD



Extra Revision Pearls

•    OCD may present in children; consider PANDAS 

                    (Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections) if sudden onset.

•    In OCD, compulsions are usually performed to prevent feared event, not for pleasure.

•    BDD patients often seek dermatological or surgical interventions poor outcomes without psychological treatment.

•    Trichotillomania and hoarding now classified under OCD-related disorders in DSM-5.

•    Insight varies: poor insight worse prognosis and poorer treatment response.

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Author & Educational Disclaimer


Author:

Dr Phillip Cockrell BM FRCP DipClinEd


Dr Phillip Cockrell is a UK Consultant Physician in Internal Medicine, currently working at Queen Alexandra Hospital, Portsmouth University Hospitals NHS Trust. He has previously worked as a registrar across Intensive Care Medicine, Gastroenterology, Cardiology, Stroke Medicine, Acute Medicine, and Respiratory Medicine.


He has held senior leadership roles including Associate Clinical Director of the Acute Medical Unit, Clinical Director of Internal Medicine, and Chief of Medicine. Dr Cockrell has over 15 years’ experience in postgraduate medical education, having lectured extensively across the MRCP syllabus and contributed to MRCP revision teaching and course development.


Dr Cockrell holds a Bachelor of Medicine (BM), Fellowship of the Royal College of Physicians (FRCP), and a Diploma in Clinical Education (DipClinEd). His teaching approach is based on structured consolidation of complex medical topics to support efficient and effective revision for postgraduate examinations.


Purpose of this content:

The material on this page is intended solely for educational purposes to support revision for the MRCP (UK) Part 1 examination. It reflects examination-relevant principles of internal medicine and is designed to aid learning and pattern recognition.


Medical disclaimer:

This content is designed for postgraduate medical examination revision and does not constitute medical advice, diagnosis, or treatment guidance and must not be used as a substitute for professional clinical judgement, local guidelines, or specialist consultation. Clinical decisions should always be made in the context of individual patient circumstances and current national guidance.